Membranous Nephropathy and Pulmonary Alveolar Proteinosis
スポンサーリンク
概要
- 論文の詳細を見る
A 47-year-old woman with a severe cough and high-grade fever demonstrated proteinuria of 3.2 g/day. Chest radiograph and CT scan revealed scattered small nodules and ground-glass opacities with interlobular septal thickening in both lungs. The serum levels of surfactant A, surfactant D, and KL-6 were increased to 190 ng/ml (normal: 0-43.8), 360 ng/ml (normal:0-110), and 4850 U/ml (normal: 0-500), respectively. Video-assisted thoracoscopic lung biopsy revealed eosinophilic amorphous material within alveoli and thickened alveolar septa, which is compatible with pulmonary alveolar proteinosis. Kidney biopsy exhibited membranous nephropathy (Stage I-II) accompanied by granular IgG deposition along the glomerular basement membrane. Although the patient refused treatment with granulocyte macrophage colony stimulating factor (GM-CSF) for pulmonary alveolar proteinosis, her proteinuria and the pulmonary lesion gradually diminished and disappeared after one year.
著者
-
Yamada Harutaka
Division Of Nephrology And Rheumatology Department Of Internal Medicine Aichi Medical University Sch
-
Kitagawa Wataru
Division Of Nephrology And Rheumatology Department Of Internal Medicine Aichi Medical University Sch
-
Miura Naoto
Division Of Nephrology And Rheumatology Department Of Internal Medicine Aichi Medical University Sch
-
Imai Hirokazu
Division Of Nephrology And Rheumatology Department Of Internal Medicine Aichi Medical University Sch
-
Nishikawa Kazuhiro
Division Of Nephrology And Rheumatology Department Of Internal Medicine Aichi Medical University Sch
-
KITAGAWA Wataru
Division of Nephrology and Rheumatology, Department of Internal Medicine, Aichi Medical University School of Medicine
-
Kashima Yukari
Division of Nephrology and Rheumatology, Department of Internal Medicine, Aichi Medical University School of Medicine
-
Matsui Seiko
Division of Respiratory Medicine and Allergology, Department of Internal Medicine, Aichi Medical University School of Medicine
-
Ozeki Norio
Department of Anatomy, Aichi Medical University School of Medicine
関連論文
- Estimation of glomerular filtration rate by the MDRD study equation modified for Japanese patients with chronic kidney disease
- Tonsillectomy and steroid pulse (TSP) therapy for patients with IgA nephropathy : a nationwide survey of TSP therapy in Japan and an analysis of the predictive factors for resistance to TSP therapy
- Adenolipoma of the Thyroid Gland : Report of a Case
- Hypocomplementemic Urticarial Vasculitis Syndrome is Associated with High Levels of Serum IgG4: A Clinical Manifestation that Mimics IgG4-related Disease
- Complement-Mediated Renal Injury: Mechanisms and Role of Membrane Regulators of Complement
- An IgA1-lambda-type monoclonal immunoglobulin deposition disease associated with membraneous features in a patient with chronic hepatitis C viral infection and rectal cancer
- Massive proteinuria and acute renal failure after oral bisphosphonate (alendronate) administration in a patient with focal segmental glomerulosclerosis
- Membranous Nephropathy and Pulmonary Alveolar Proteinosis
- The increase of antiglomerular basement membrane antibody following pauci-immune-type crescentic glomerulonephritis
- Diminished Numbers of Natural Killer Cells in the Sentinel Lymph Nodes of Patients with Non-Small Cell Lung Cancer
- A case of chronic kidney disease with thrombotic microangiopathy in a hematopoietic stem cell transplant recipient
- Torsades de Pointes induced by a combination of garenoxacin and disopyramide and other cytochrome P450, family 3, subfamily A polypeptide-4-influencing drugs during hypokalemia due to licorice
- Acute peritonitis due to Corynebacterium ulcerans in a patient receiving continuous ambulatory peritoneal dialysis : a case report and literature review
- Thrombotic thrombocytopenic purpura in a patient with rapidly progressive glomerulonephritis with both anti-glomerular basement membrane antibodies and myeloperoxidase anti-neutrophil cytoplasmic antibodies
- Myeloperoxidase-antineutrophil cytoplasmic antibody-related crescentic glomerulonephritis after treatment for clinically amyopathic dermatomyositis : a coincidental combination or not?
- Progressive renal failure despite long-term biweekly enzyme replacement therapy in a patient with Fabry disease secondary to a new α-galactosidase mutation of Leu311Arg (L311R)
- A large-sized bubbling appearance of the glomerular basement membrane in a patient with pulmonary limited AL amyloidosis and a past history of lupus nephritis
- Extracellular-Superoxide Dismutase Expression in COS7 Cells Exposed to Cadmium Chloride
- Proteinase 3 Anti-Neutrophil Cytoplasmic Antibody (PR3-ANCA) Positive IgG4-Related Retroperitoneal Fibrosis: Utility of PET-CT with 18F-Fluorodeoxy Glucose (FDG)
- Myeloperoxidase Anti-cytoplasmic Antibody Related Crescentic Glomerulonephritis in a Patient with IgG3λ Monoclonal Immunoglobulin Deposition Disease with Membranous Features
- A treatment dilemma in adult immunoglobulin A nephropathy : what is the appropriate target, preservation of kidney function or induction of clinical remission?
- Clinicopathological Analysis of Glomerulopathy with Fibronectin Deposits (GFND): A Case of Sporadic, Elderly-Onset GFND with Codeposition of IgA, C1q, and Fibrinogen