Successful Treatment of a Mesangial Proliferative Glomerulonephritis with Interstitial Nephritis Associated with Castleman's Disease by an Anti-interleukin-6 Receptor Antibody (Tocilizumab)
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概要
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We report a case of mesangial proliferative glomerulonephritis with interstitial nephritis associated with multicentric Castleman's disease (MCD) successfully treated with an anti-interleukin-6 receptor antibody (tocilizumab). This mesangial proliferative glomerulonephritis with interstitial nephritis was resistant to methylprednisolone treatment; however, it was markedly improved with tocilizumab, which was administered intravenously at a dose of 8 mg/kg every 2 weeks. These results suggest that tocilizumab is effective for the treatment of mesangial proliferative glomerulonephritis with interstitial nephritis associated with MCD.
- 社団法人 日本内科学会の論文
著者
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Kusano Eiji
Division Of Nephrology Department Of Internal Medicine Jichi Medical School
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Muto Shigeaki
Division Of Nephrology Department Of Internal Medicine Jichi Medical School
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Morishita Yoshiyuki
Division Of Nephrology Department Of Medicine Jichi Medical University
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Takemoto Fumi
Division Of Nephrology Department Of Internal Medicine Jichi Medical University
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Otani Naoko
Division Of Nephrology Department Of Internal Medicine Jichi Medical University
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Saito Osamu
Division Of Nephrology Department Of Internal Medicine Jichi Medical University
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Oh Iekuni
Division of Cell Therapy, Jichi Medical University Hospital, Shimotsuke
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Oh Iekuni
Division of Hematology, Department of Internal Medicine, Jichi Medical University, Japan
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