Anti-Glomerular Basement Membrane Glomerulonephritis Complicated by Thrombocytopenia

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概要

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• Rapidly progressive glomerulonephritis (RPGN) is characterized by the rapid deterioration of the renal function associated with crescent formation on renal biopsies. This report describes a case of RPGN caused by anti-glomerular basement membrane (GBM) glomerulonephritis in an elderly man with severe thrombocytopenia and a platelet count of 1.4×104/μL. Thrombotic microangiopathy (TMA) and heparin-induced thrombocytopenia (HIT) were implicated in the severe decrease in platelets. This report also discusses the pathological background and clinical management of TMA and HIT among patients with anti-GBM glomerulonephritis.

著者

• Akimoto Tetsu

  Division Of Nephrology Department Of Internal Medicine Jichi Medical School

• Kusano Eiji

  Division Of Nephrology Department Of Internal Medicine Jichi Medical School

• Muto Shigeaki

  Division Of Nephrology Department Of Internal Medicine Jichi Medical School

• Morishita Yoshiyuki

  Division Of Nephrology Department Of Medicine Jichi Medical University

• Miki Takuya

  Division Of Nephrology Department Of Medicine Jichi Medical University

• Iwazu Yoshitaka

  Division Of Nephrology Department Of Internal Medicine Jichi Medical University

• Otani Naoko

  Division Of Nephrology Department Of Internal Medicine Jichi Medical University

• Numata Akihiko

  Division Of Nephrology Department Of Internal Medicine Jichi Medical University

• Sugase Taro

  Division Of Nephrology Department Of Internal Medicine Jichi Medical University

• Takeshima Eri

  Division Of Nephrology Department Of Internal Medicine Jichi Medical University

• Numata Akihiko

  Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan

• Sugase Taro

  Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan

• Otani Naoko

  Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Japan

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