Pulmonary veno-occlusive disease following reduced-intensity allogeneic bone marrow transplantation for acute myeloid leukemia
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概要
- 論文の詳細を見る
We report a case of pulmonary veno-occlusive disease (PVOD) following allogeneic bone marrow transplantation (BMT) for the treatment of acute myeloid leukemia (AML) from an HLA mismatched mother using a reduced-intensity conditioning (RIC) regimen including gemtuzumab ozogamicin. The patient was a 21-year-old male who complained of dyspnea with hypoxemia followed by loss of consciousness. The abnormalities in chest CT and echocardiography were compatible with a diagnosis of PVOD. Treatment with 1 mg/kg of oral prednisolone resolved dyspnea and hypoxemia within a few days, and chest CT abnormalities disappeared in a week. This report is the first to describe PVOD following RIC stem cell transplantation. © 2012 The Japanese Society of Internal Medicine.
著者
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Kobayashi Satoshi
Department of Aging Medicine and Geriatrics, Shinshu University, Graduate School of Medicine
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Fujimura Masaki
Cellular Transplantation Biology Department Of Respiratory Medicine Kanazawa University Graduate Sch
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Takami Akiyoshi
Cellular Transplantation Biology Kanazawa University Graduate School Of Medical Science
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YAMAZAKI Hirohito
Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science
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Nakao Shinji
Cellular Transplantation Biology Department Of Respiratory Medicine Kanazawa University Graduate Sch
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Fujimura Masaki
Pulmonary Medicine Cellular Transplantation Biology Kanazawa Graduate School Of Medicine
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藤村 政樹
金沢大学大学院医学系研究科細胞移植学・呼吸器内
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Hosokawa Kohei
Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Japan
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Takami Akiyoshi
Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Japan
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Nakao Shinji
Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Japan
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Kobayashi Satoshi
Department of Radiology, Kanazawa University School of Medicine, Japan
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Nishitsuji Masaru
Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Japan
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