An Assessment Method of Clinical States in Bacterial Pneumonia

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Patients with pneumonia have a variety of symptoms such as dyspnea, cyanosis, cough, rales, fever, chest pain, leukocytosis, increase of erythrocyte sedimentation rate, all of which do not appear, deteriorate or improve in a parallel manner. For making objective assessments in adequate and well controlled clinical investigations, it is favorable to use a rating scale which is well characterized both by the assessment criteria of the individual symptoms and by the investigation on the relationship between the various symptoms. Although some works on this subject have been done, the assessment method is not well established.<BR>In this paper, data on 72 cases with bacterial pneumonia being applied, assess ment criteria for chest X-ray films is discussed, and factor analytic approach is adopted to examine the basic structure of symptoms including findings on X-ray films. Three factors were extracted, each of which was characterized by a corresponding group of symptoms such as cyanosis, rales etc. for the first factor, cough and sputum for the second, fever and other general symptoms for the third. It was turned out that the first followed by the second symptom group showed speedy recovery, whereas improvement of the third group was clearly delayed; the disappearance ratio after two-week treatment was 78.6%, 81.8%, 13.9% in the first, second and third symptom group respectively. Correlation of subjective global judgement with these characteristic inclinations of each symptom group observed here was also investigated, and finally, a tentative rating scale for the assessment of chemotherapy on pneumonia is proposed.
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An Assessment Method of Clinical States in Bacterial Pneumonia

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