選択的近位迷走神経切離後の胃内容排泄動態の変化

概要

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The patterns of gastric emptying after selective proximal vagotomy (SPV) and SPV with pyloroplasty (SPV+D) were studied using a liquid labelled with 99mTc-DTPA. By means of on-line computer facility, it was possible to analyse the relative role of the Whole stomach and the antrum within the overall frame work of gastric emptying. In the time/activity curve of the whole stomach, all of 3 groups emptied in exponential curve. Comparing with normal subjects, SPV subjects were tending to empty slowly, while SPV+D subjects were tending to empty rapidly. In the time/activity curve of the antrum, normal and SPV+D subjects had two types of emptying-one was represented in the decreasing curve and another was represented in the increasing-decreasing curve. While SPV subjects had only one type of emptying which was represented in the increasing-decreasing curve. From a consideration of the pattern of gastric emptying curve, SPV subjects had two different emptying states compared with normal subjects-one was the delay of entering the antrum from the fundic side of stomach, and the other was that effective antral emptying did not readily start. While SPV+D kept more neally normal gastric emptying that it of SPV.