EXPERIMENTAL STUDIES OF INTESTINAL INTUSSUSCEPTION

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For this experiment, paraffin induced phyma, shrunk phyma and artificial intussusception were produced at the terminal ileum of infant dogs .<BR>The development process of intestinal intussusception was traced in the dogs affected with the above types of phyma and macroscopic observation as well as record of action potential of smooth muscles, were made of the artificial intussusception to examine intestinal movements contributing to the progressive dynamics of intestinal canal intussusception. The experiment revealed the followings;<BR>1. Intestinal intussusception failed to develop from artificial phymas on the intestinal wall. This was because the intussusception did not create a stimulating factor to influence intestinal movements .<BR>2. Macroscopic observation of artificial intussusception revealed a characteristic increase of the retraction ring on the external canal of the intussuscepted portion, suggesting accentuation of external canal movements.<BR>Measurement of action potential of smooth muscles disclosed almost negative potential in the internal canal, and decrease in the proximal portion of intestinal canal. On the other hand, action potential of the external canal manifested an increase for a prolonged period, which showed that the external intestinal canal was contributing greatly to the progress of the intestinal intussusception.
日本平滑筋学会の論文