救命丸の動物実験ならびに団地居住小児における連用成績

概要

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Investigation was made on pharmaceutical potency and side effects of the herb medicine "Kyumeigan". The results obtained are as follows. 1. Single oral administration of each active component of this drug to mice in a dose of 100 mg per kg brought about no appreciable change in the body-weight curves. LD<SUB>50</SUB> of the compound preparation "Kyumeigan" was 3170 mg/kg. 2. In 96 children of the age more than a year but less than 5, the administration in the indicated dosage for 6 months induced no side effects. 3. In 75 children among the 95), who had some constitutional defects, a value of 60% was odtained for the improvement of conditions, and a remarkable effects was also obtained especially in the cases of gastrointestinal adynamia, nerve erethism and enuresis nocturna.
日本民族衛生学会の論文