A convenient synthesis of 2-acylmethyl-4,4-dimethyl-2-oxazolines. Useful reagents for .BETA.-keto ester synthesis.
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概要
- 論文の詳細を見る
Acylation of 2,4,4-trimethyl-2-oxazoline with acid chlorides having no α-proton and triethylamine gave <I>C</I>,<I>N</I>-diacylated products. Hydrolysis of the products with potassium hydroxide gave the enols of 2-acylmethyl-oxazolines, which were selectively <I>C</I>-monoalkylated by alkyl halides.
- 公益社団法人 日本化学会の論文
著者
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TOHDA Yasuo
Department of Chemistry, Osaka Kyoiku University
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Ariga Masahiro
Department Of Chemistry Osaka Kyoiku University
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Mori Yutaka
Department Of Applied Chemistry Graduate School Of Engineering Osaka City University
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Kawashima Toshihide
Department of Chemistry, Osaka Kyoiku University
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Akiyama Ryohei
Department of Chemistry, Osaka Kyoiku University
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Shudoh Hiroshi
Department of Chemistry, Osaka Kyoiku University
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