Synthesis of pyranoisoflavones from pyronochalcones: Synthesis of elongatin and its angular isomer.
スポンサーリンク
概要
- 論文の詳細を見る
Elongatin (4′,5-dihydroxy-2′,5′-dimethoxy-2″,2″-dimethylpyrano[5″,6″-g]isoflavone) was synthesized by an oxidative rearrangement of the corresponding pyronochalcone [6-(1-oxo-3-phenyl-2-propenyl)-4-chromanone] with thallium(III) nitrate and a regioselective reduction of 7-(4-benzoyloxy-2,5-dimethoxyphenyl)-2,3-dihydro-2,2-dimethyl-5-tosyloxy-4<I>H</I>,6<I>H</I>-benzo[1,2-<I>b</I>:5,4-<I>b</I>′]dipyran-4,6-dione with sodium boronydride–palladium chloride, followed by dehydration of the resultant alcohol and hydrolysis. Its angular isomer (4′,5-dihydroxy-2′,5′-dimethoxy-2″,2″-dimethylpyrano[6″,5″-<I>h</I>]isoflavone) was also synthesized from the corresponding pyronochalcone in a similar manner.
- 公益社団法人 日本化学会の論文
著者
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Tamaki Hiroto
Department Of Applied Chemistry Faculty Of Engineering Tokushima University
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KAWAMURA Yasuhiko
Department of Chemical Science and Technology, Faculty of Engineering, The University of Tokushima
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Horie Tokunaru
Department of Applied Chemistry, Faculty of Engineering, Tokushima University
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Kawamura Yasuhiko
Department Of Chemical Science And Technology Faculty Of Engineering The University Of Tokushima
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Tsukayama Masao
Department Of Biological Science And Technology The University Of Tokushima Graduate School
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HORIE Tokunaru
Department of Chemical Science and Technology, Faculty of Engineering, The University of Tokushima
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Kubo Tomoya
Department of Chemical Science and Technology, Faculty of Engineering, The University of Tokushima
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Kawamura Yasuhiko
Department of Applied Chemistry, Faculty of Engineering, Tokushima University
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Tamaki Hiroto
Department of Chemical Science and Technology, Faculty of Engineering, The University of Tokushima
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