Microbiosensing device for real time determination.

概要

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A microbiosensing device fabricated by assembling an enzyme-embodied microelectrode with a counter electrode and a reference electrode was applied to the real time determination of trace droplet of glucose sample. The microdevice demonstrated unique properties such as real time response, independence of sample volume, unnecessity of sample mixing by the rendezvous of microfabricated biosensing device with pulse voltammetry. A linear relationship between sensor output and glucose concentration was obtained in the concentration range from 10−3 to 10−1 mol L−1. The sensing device responded to every glucose sample of different concentration in 2 ms, and the coefficient of variation for 10 mM glucose determination was within 5%.
公益社団法人日本化学会の論文