Intramolecular Cycloaddition of the Azomethine Ylides Derived from α-Amino Acids or Esters and 5-Oxo-6-heptenals or 4-Oxo-5-hexenals
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概要
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Intramolecular cycloadditions of the azomethine ylides bearing a carbonyl-activated olefinic moiety, generated from α-amino acids or esters and 5-oxo-6-heptenals or 4-oxo-5-hexenals, produce the stereoselective internal cycloadducts either to olefin or carbonyl dipolarophilic function with normal or inverse regioselectivity, depending upon the types of ylides as well as the intervening chain length. Exclusively high diastereofacial selectivity has been achieved when 2-phenyl-4-thiazolidinecarboxylic acid and its methyl ester are utilized.
- 公益社団法人 日本化学会の論文
著者
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Kanemasa Shuji
Institute Of Advanced Material Study Kyushu University
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Wada Eiji
Institute Of Advanced Material Study Kyushu University
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Doi Kenji
Department of Hospital Pharmacy, Nagasaki University Hospital of Medicine and Dentistry
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Doi Kenji
Department of Molecular Science and Technology, Interdisciplinary Graduate School of Engineering Sciences, Kyushu University
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