Synthesis of Some Nucleoside Analogs of Substituted 1,2,3-Triazole
スポンサーリンク
概要
- 論文の詳細を見る
1-(β-D-Ribofuranosyl)-1,2,3-triazole-4-carboxamide (<B>4</B>) and 4-amino-1-(β-D-ribofuranosyl)-1,2,3-triazole-5-carboxamide (<B>7</B>) have been synthesized as an approach to obtain bioisosteres of pyrazomycin, an antiviral agent. The synthesis has been accomplished by condensation of blocked triazoles with tri-<I>O</I>-benzoyl-D-ribofuranosyl chloride in the presence of mercuric cyanide in nitromethane. UV spectral studies revealed the orientation of <I>N</I>-glycosidation in the substituted triazoles.
- 公益社団法人 日本化学会の論文
著者
-
Umezawa Sumio
Department of Applied Chemistry Engineering Faculty Keio University
-
Fukatsu Shunzo
Department of Applied Chemistry, Faculty of Engineering, Keio University
-
Makabe Osamu
Department of Applied Chemistry, Faculty of Engineering, Keio University
関連論文
- Studies on Antibiotics and Related Substances. XV. Syntheses of Acetobromo Derivatives of 3-Amino-3-deoxyglucose and 6-Amino-6-deoxyglucose
- Studies on Antibiotics and Related Substances. X. Syntheses of Some Unsaturated Ketocarboxylic Acids, Anti-tumor Substances
- Studies on Antibiotics and Related Substances. XVII. Syntheses of trans-2-Aminocyclohexyl-D-glucosaminides
- Studies on Antibiotics and Related Substances. XI. Methylated Amino-sugar Moieties from Methylated Kanamycin
- Synthesis of Di-N-acetyl-di-N-benzyloxycarbonyl-O-cyclohexylidenestreptidine
- Syntheses of (3S, 4R, 15S)-4,15-Dimethyl-1,5-dioxa-3-(3′-formamidosalicylamido)-cyclopentadecane-2,6-dione and Its (15R)-Epimer, New Antimycin Analogs
- Studies on Aminosugars. XXXVI. Syntheses of 3′,4′-Dideoxy-and 3′,4′,5″-Trideoxyribostamycin
- Synthesis of 6′-Amino-1-N-[(S)-4-Amino-2-Hydroxybutyryl]-6′-Deoxylividomycin A
- Studies on Aminosugars. XXXV. Syntheses of 3′,4′-Dideoxyneamine and 3′- and 4′-O-Methylneamines
- Studies on Aminosugars. XXIX. Syntheses of Nucleosides of 3-Amino-3-deoxy-3-C-hydroxymethyl-β-D-ribofuranose
- Synthesis of Butirosin B and Its 3′,4′-Dideoxy Derivative
- Synthesis of "Reversed" Nucleosides of Some Purine and Pyrimidine Bases
- Studies on Aminosugars. XXX. The Synthesis of 3′-Deoxykanamycin
- Synthesis of 6-(2-Amino-2-deoxy-β-D-glucopyranosylamino)- and 6-(β-D-Glucopyranosylamino)purine
- Synthesis of Some Nucleoside Analogs of Substituted 1,2,3-Triazole
- Studies on Aminosugars. XXXI. Synthesis of 3,4-Dideoxy-3-enosides and the Corresponding 3,4-Dideoxysugars
- Synthesis of Cyclic α-Amino Acids. IV. Syntheses of Adenine Nucleosides of 3-Amino-3-C-carboxy-3-deoxy-D-ribofuranose and 3-Amino-3-C-carboxy-3-deoxy-D-ribopyranose
- Studies on Aminosugars. XXIV. The Facile Elimination of the Derivatives of a Pyranosid-4-ulose
- Total Syntheses of Antimycin A3 and Its Diastereomer