婦人科における抗癌剤レジメン(卵巣癌治療の現状)

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We have treated 132 patients with ovarian cancer January 1983 and December 1988, we will introduce our treatment and explain the problems of manegement.<BR>The standard operative procedure is bilateral salpingooophorectomies, abdominal hysterectomy and partial omentectomy, and CDDP intraperitoneal medication. Patients over stage lc fitst lins chemotherapy is practiced. CAP or CP for epithelial ovarian cancer and PEP or PVP for germinol cell ovarian cancer. Second line chemotherapy is EP.<BR>The five-year survival rates for primary ovarian cancer were 88.9% for stage I,87.5% for stage II,53.3% for stage III,16.7% for srage IV, no significant difference was found between hystorgical group. Early patients were treated with FAM, and later patients with CAP. For stageIII, five year survival rate was 28.5% with FAM, and 75% with CAP, a significant difference.<BR>Reccurent patients and uncontrolled tumors after first line chemotherapy were treated with EP, there was very poor response to second line chemotherapy. Patients over stage lc are high risk group of reccurent, and first line chemotherapy must be done completly.
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