Myocardial Involvement in Patients With Osteogenesis Imperfecta
スポンサーリンク
概要
- 論文の詳細を見る
Mitral and aortic valve regurgitation is commonly found in osteogenesis imperfecta (OI) patients, however, little is known about the myocardial involvement in this disorder. An 82-year-old man with OI developed heart failure and was admitted to our hospital. Echocardiogram revealed severe mitral regurgitation without left ventricular (LV) dilatation, but with LV wall thickening. Histological analysis exhibited interstitial fibrosis of the myocardium in addition to myxoid changes of the mitral leaflet. These findings suggest that OI patients may develop LV remodeling together with diastolic dysfunction.
著者
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Fujiu Katsuhito
Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
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Semba Hiroaki
Department of Cardiovascular Internal Medicine, The Cardiovascular Institute
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Takeda Norihiko
Department Of Applied Chemistry Faculty Of Engineering Osaka University
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Abe Hajime
Department Of Applied Physics Graduate School Of Engineering Osaka University
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Hirata Yasunobu
Department Of Advanced Clinical Science And Therapeutics Cardiovascular Medicine Graduate School Of
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Takazawa Yutaka
Department Of Cardiothoracic Surgery And Human Pathology The University Of Tokyo Graduate School Of
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Fujiu Katsuhito
Department Of Cardiology The University Of Tokyo
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Nagai Ryozo
Department Cardiovascular Medicine The University Of Tokyo Hospital
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Fukayama Masashi
Department Of Diagnostic Pathology Kanto Teishin Hospital
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Yamashita Hiroshi
Department Of Cardiovascular Medicine Graduate School Of Medicine University Of Tokyo
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KOJIMA Toshiya
Department of Cardiovascular Medicine, University of Tokyo Graduate School of Medicine
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Takeda Norihiko
Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
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Soma Katsura
Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
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Shintani Yukako
Department of Pathology, Faculty of Medicine, The University of Tokyo
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Semba Hiroaki
Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
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Kojima Toshiya
Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
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