Cytotoxic Terpenes from the Stems of Dipterocarpus obtusifolius Collected in Cambodia
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概要
- 論文の詳細を見る
From the stems of Dipterocarpus obtusifolius, five new triterpenes, 3-oxo-20-hydroxy-30α-methyl,17(29)α-epoxy-28-norlupane (1), 3-oxo-20-hydroxy-30β-methyl-17(29)α-epoxy-28-norlupane (2), 3,20-dioxo-28,29-norlupan-17α-ol (3), 27-demethyl-20(S)-dammar-23-ene-20-ol-3,25-dione (4), and 3-epi-cecropic acid (5) together with 13 known compounds including diterpene, sesquiterpenes and triterpenes were isolated and characterized. All isolates were tested for their cytotoxicities against a small panel of human cancer cell lines. Of the tested compounds, compounds 4–11 were found to be cytotoxic against one or more human cancer cell lines.
- 公益社団法人 日本薬学会の論文
著者
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Chin Young-won
College Of Pharmacy And Research Institute Of Pharmaceutical Science Seoul National University
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Khiev Piseth
University of Science & Technology
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Lee Hyeong-Kyu
University of Science & Technology
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Kwon Ok-Kyoung
Natural Medicine Research Center, Bio-Therapeutics Research Institute, Korea Research Institute of Bioscience & Biotechnology (KRIBB)
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Song Hyuk-Hwan
Natural Medicine Research Center, Bio-Therapeutics Research Institute, Korea Research Institute of Bioscience & Biotechnology (KRIBB)
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Oh Sei-Ryang
University of Science & Technology
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Ahn Kyung-Seop
Natural Medicine Research Center, Bio-Therapeutics Research Institute, Korea Research Institute of Bioscience & Biotechnology (KRIBB)
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Oh Sei-Ryang
University of Science & Technology
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Ahn Kyung-Seop
Natural Medicine Research Center, Bio-Therapeutics Research Institute, Korea Research Institute of Bioscience & Biotechnology (KRIBB)
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Lee Hyeong-Kyu
University of Science & Technology
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Kwon Ok-Kyoung
Natural Medicine Research Center, Bio-Therapeutics Research Institute, Korea Research Institute of Bioscience & Biotechnology (KRIBB)
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Khiev Piseth
University of Science & Technology
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Ahn Kyung-Seop
Natural Medcine Research Center, Korea Research Institute of Bioscience & Biotechnology
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Kwon Ok-Kyoung
Natural Medcine Research Center, Korea Research Institute of Bioscience & Biotechnology
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