末梢性顔面神経麻痺に対するメチコバ-ルの効果について--回帰直線を用いて

概要

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Rating paralysis score (YANAGIHARA, 1976) is an excellent psychometric method for clinician to estimate degree of facial paralysis. In addition to this, integrated EMG method proposed by YAGI, et al. (1979) also gives an additional electromyographic information of affected facial muscles. When we use both paralysis score and integ. EMG, we can easily follow recovery process of facial paralysis expressed as increase of score and percentage of integ. EMG. Both increases are almost linear to daily recovery of paralysis, and could be plotted in semilogarithmic paper as a linear line. By applying regression analysis to this, it is possible to calculate and determine slope and constant of following equation:Y=Blogx-AY: score x: day B: slope A: constantIn equation, slope means speed of recovery such as recovery become rapid when it is high.In 29 cases of peripheral facial paralysis, the effect of methycobalgroup (12 cases) and steroid group (17 cases) was compaired after calculation of each regression line in all cases. As to slope, methycobal group and steroid group were 80.07, 92.21 respectively and showed no significant difference statistically.This means that methycobal has same effect as steroid on treatment of facial paralysis.
耳鼻咽喉科臨床学会の論文