上顎洞および鼻腔にポリ-プ状腺癌を合併したPeutz-Jeghers症候群の1症例 (天理よろづ相談所病院耳鼻咽喉科開設15周年記念論文集)

概要

論文の詳細を見る
We began to treat this case under the diagnosis of maxillary carcinoma from X-ray finding and inspection, but did not recognized malignancy in pathological examination. After reconsideration, we hit upon Peutz-Jeghers Syndrome from past history and pigmentation around the lip. This syndrome is said to be often associated with the following three signs: (1) pigmentation of melanin around the lip, at the mucosal membrane of the oral cavity, and on the fingers and toes, (2) polyposis of the alimentary tract, chiefly at the small intestine, and (3) hereditary disposition. In postoperative prognosis, polyplike tumor recured in hard palate after 1.5 years. Pathological finding was similar to last time, but we recognized infiltration to bone, disorder of cells arrangement, and increase of atypia. Then we diagnosed this tumor as adenocarcinoma. We have so far been informed of three reports in whom polyp took place at the nose ascide from the alimentary tract, but they were all reported from other departments, and details were unknown. This syndrome has been reported here as it is not generally known as a syndrome related with otorhinolaryngology.