Effect of Nicergoline on Vertigo and Tinnitus.

概要

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Nicergoline is a synthetic alkaloid with many effects on the CNS. Forty six patients suffering from vertigo and tinnitus were treated with nicergoline in a dose of 15 mg/day for four or eight weeks. The efficacy of the drug in the reduction of vertigo was marked improvement in 11.1%, marked or moderate improvement in 62.5% and slight to marked improvement in 88.9% at four weeks. At eight weeks there was marked improvement in 6.7%, marked or moderate improvement in 66.7% and slight to marked improvement in 100%. At four weeks tinnitus was markedly reduced in 5%, markedly or moderately reduced in 20.0% and slightly to markedly reduced in 65.0%. At eight weeks the corresponding figures were 7.9%, 61.5% and 92.3%. Only one patient complained of some side effect. The results suggest that nicergoline is a safe and clinically useful drug for the treatment of vertigo or tinnitus.
耳鼻咽喉科臨床学会の論文