Autoimmune inner ear dysfunction in Harada disease.

概要

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Vogt-Koyanagi-Harada disease is an autoimmune disorder involving melanocytes in the eye, ear, skin and meninges. We report a 35-year-old female who complained tinnitus, fluctuating hearing loss and vertigo following sudden onset of uveitis. Neurotological examinations revealed that these ear symptoms were of inner ear origin, and her clinical course resembled that of Meniere's disease. These clinical findings suggested that the dysfunction of the inner ear is caused by endolymphatic hydrops, which resulted from autoimmune response against melanocytes.
耳鼻咽喉科臨床学会の論文