intravagal paragangliomaの3症例

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We describe three cases of intravagal paraganglioma and review the literature on clinical and histological findings and treatment. Our patients ranged in age from 36 to 46 years (mean, 40 years old); two males and one female.All three patients had a large parapharyngeal mass, and paralysis of the reccurent laryngeal nerve was noted in two of them. At surgery the tumors were found to be very close to the vagus nerve. However, the carotid bifurcation was not widened. Postoperative irradiation (60 Gy) was performed in one case because the tumor was unresectable. All tumors demonstrated similar histological characteristics. They were highly vascularized and had prominent hyalinized collagenous septa. An alveolar pattern was produced by the reticulin network. Each tumor cell had an ovoid or round nucleus and eosinophilic cytoplasm. Cytoplasmic argyrophil granules were demonstrated by the Grimelius stain, proving the tumors to be paragangliomas.
耳鼻咽喉科臨床学会の論文