Clinical use of pulsatile cardiopulmonary bypass system for infants.

概要

論文の詳細を見る
Developing pulsatile cardiopulmonary bypass (CPB) system for infants, experimental and clinical studies were done. In experiments of 5 dogs, pulsatile (PF) and steady (SF) flow perfusion were exchanged every 20min. in each dogs. Systemic vascular resistance (SVR) in PF was significantly lower than in SF. Renal blood flow in PF significantly showed higher than in SF. At the same level of mean blood pressure, renal blood flow in PF was significantly higher than in SF. One hundred and twenty one clinical cases were performed open heart operations by this system. Ninety four of 121 cases were mainly perfused by PF. These age were ranged 2 days-10 years old, weight were 2.2-26.0Kg and perfusion time were 22-272min. Comparing with clinical data in PF (n=10) and SF (n=12), Jatene's operations were studied. SVR in PF significantly showed lower than in SF. Systemic venous return in PF was significantly better than in SF. There was no problem during open heart operation using this system.
一般社団法人日本人工臓器学会の論文