Acute effect of elevated intracompartmental pressure on muscle blood flow.

概要

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An animal model of the compartmental syndrome is presented to study the acute effect of elevated intracompartmental pressure on muscle blood flow. Latex balloon was inserted into the anterior compartment of rabbits and the pressure was controlled by an adjustable water column. The slit catheter technique wes employed for continuous pressure monitoring of the compartment. Blood flow to the muscle of the compartment was determined using the hydrogen washout technique, which allowed repeated blood flow measurements. At pressures between 22 and 56 millimeters of mercury, blood flow to the muscle was found to be completely stopped in all animals. The percentage of the critical pressures of the compartment as compared to the systolic pressures of the femoral artery ranged from 22 to 51 percent with an average of 42.2 percent. The results in these experiments helped to identify a critical pressure at which fasciotomy should be performed in patients with a threatened compartment syndrome.