血漿コレステロ-ルに関する比較生化学的研究-1-コイ血漿レシチン:コレステロ-ルアシルトランスフェラ-ゼ活性について〔英文〕

概要

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Although there is quite a few data available on the esterification of cholesterol in land animals, almost no research is available on fishes. In the present paper, the plasma lecithin: cholesterol acyltransferase (LCAT) activities of carp, Cyprinus carpio, were measured under the normal, starved, and diabetic conditions. Its optimum pH was around 6.5-7.0 and the maximum activity was obtained at 37°C in the experimental condition. The LCAT activity of starved carp was about 50% higher than that of the control In the diabetic case, the LCAT activity increased approximately 80%. Generally, the LCAT activity as well as the proportion of cholesterol esters in the plasma of carp are less than those of man, suggesting somewhat different structure of lipoproteins which trans-port free and esterified cholesterols with other lipid components.
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