INFECTION OF MYCOBACTERIA WITH MYCOBACTERIOPHAGE抗酸菌ファージの感染に関する研究 : 2. 抗酸菌ファージB-1株の抗酸菌7株への感染時間

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Six tenths per cent of Sodium hydroxide was used to estimate the time required for the ad sorption-invasion of mycobacteriophage B-1 strain to 7 strains of mycobacteria which had different generation time and different latent period in infection with the same phage. Mycobacteria used were M. smegmatis, atypical mycobacterium P-17, P-18, P-22, P-40, P-44 and Mycobacterium tuberculosis var. hominis H37Ra. The results obtained are summarized as follows. 1) B-1 Phage was adsorbed on and invaded into the host cells within 30 sec after mixing the phages and the host cells. 2) Adsorption-invasion time was the same in all the mycobacterial phage and host systems used. 3) The number of plaque-formant increased logarithmically and showed the maximal value in 5 to 10 min after mixing the phages and the host cells.
日本結核病学会の論文