EFFECTS OF PENICILLAMINE ON THE CONTENTS OF B6 VITAMERS OF THE MOUSE BRAIN
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概要
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The contents of B6 vitamers were measured in the brains of mice treated with DL- and D-PeA, When a single convulsant dose of DL-PeA was injected, PLP content was decreased, being accompanied with production of PLP-thiazolidine. The effect of DL-PeA on PLP content was evident far before the occurrence of the convulsions. The administration of PN together with DL-PeA prevented the onset of seizures and lessened the effect of DL-PeA on PLP content. The same amount of D-PeA did not invoke seizures, but caused a small but significant decrease in PLP content
- 財団法人 学会誌刊行センターの論文
著者
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高橋 康子
慈恵医大医化学
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松田 誠
Department of Biochemistry, The Jikei University School of Medicine
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高橋 康子
Department o f Internal Medicine, 3rd Hospital, The Jikei University School of Medicine
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高橋 康子
Department of Biochemistry, The Jikei University School of Medicine
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