EFFECTS OF PENICILLAMINE ON DISTRIBUTION OF B6 VITAMERS IN RAT URINE
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概要
- 論文の詳細を見る
The antivitamin B6 effect of DL- and D-penicillamine has been studied in rats. A considerable elevation in the urinary excretion of vitamin B6 activity (pyridoxal and its thiazolidine derivative) has been shown as a parameter of B6 antagonism. Both DL- and D-penicillamine have been shown to have an antivitamin B6 effect in rats, although that induced by the DL-form is considerably greater, as would be expected from previous studies. We suggest that B6 supplementation should be included in any long term penicillamine therapy, regardless of the isomer that is employed.
- 財団法人 学会誌刊行センターの論文
著者
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梶原 敏英
慈恵医大 生化学
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松田 誠
Department of Biochemistry, The Jikei University School of Medicine
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梶原 敏英
Department of Orthopedic Surgery and Department of Biochemistry, Jikei University School of Medicine
関連論文
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- 1.ラット尿中のビタミンB_6に対するペニシラミン投与の影響(JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY : 掲載論文要旨)
- Effects of Penicillamine on Distribution of B6 Vitamers in Rat Urine
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- EFFECT OF SUCCINIC SEMIALDEHYDE ON SEIZURE CAUSED BY VITAMIN B6 ANTAGONISTS
- EFFECTS OF PENICILLAMINE ON DISTRIBUTION OF B6 VITAMERS IN RAT URINE
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