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Watching platelet coagulability of collagen, a microfibrillar collagen hemostat, Avitene®, was applied to 22 affected sites in 18 cases operated in our department of oral surgery with the results obtained as follows: The drug was applied to various breeding episodes including hemorrhage from soft tissue, bone and wounds after tooth extraction. The effective rate of hemostasis was 91%(more than "effective"), which was higher than other conventional hernostatics. Some difficulty may exist in the use of this drug because of its high adhesivity requiring great skill for applying, which may be however sloved by practice. Moreover, the drug has no possibility of becoming a foreign substance because of its good adhesive property and easy removal after hemostasis as compared to other conventionally used oxidized cellulose, gelatin preparations and bone wax. As a result, Avitene® is considered to be a safe and effective drug applicable to both soft and hard tissues.
社団法人日本口腔外科学会の論文