下顎から頬部・側頭下窩に及んだ軟骨肉腫の1例

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Incidences of Chondrosarcoma in the oral region are very rare. This is a case report of chondrosarcoma which originated in the mandible. The patient was a 20-years old male with chief complaint of hard swelling of the right buccal. We could not find the abnormal region, on an orthopantomogram. The results of a whole body 67Ga-citerate scintigram showed an abnormal accumulation on the right side of the face. On the CT-scan, a tumor was surrounded by his right mandible and had grown into the intratemporal fossa. But, the bone of the right sinus was intact. The histopathological diagnosis was “High grade malignancy chondrosarcoma”. After a 20 Gy of Linac irradiation, a tumor exicision with hemimandiblectomy was carried out. For access into the intratemporal fossa, the zygomatic arch was cut off. After the operation, it was returned to original position and fixed with wire. The tumor size was 60×70×50mm, and was surrounded by thin fibrastic tissue. The mandible reconstruction was carried out using A-O reconstruction plate. After the operation, adjuvant chemotherapy was given with “ADRIAMYCIN, VINCRISTINE, CYCLOPHOSPHAMIDE and PREDONINE” Chemotherapy was given 4 times every 3 or 4 months after the operation. As of now, 20 months after operation, there is no evidence of recurrence or metastasis.