Cementifying fibroma of the mandible. Report of a case with electron microscopic observation.:Report of acase with electron microscopic observation

概要

論文の詳細を見る
Cementifying fibroma is a rare neoplasm of the bone with a predilection for the mandible. We experienced a case of cementifying fibroma of the right lower posterior region of the mandible in a 61-year-old male. The tumor was surgically removed under local anesthesia. The obtained specimen was examined with light and electron microscopes.<BR>Light microscopic findings: The tumor was composed of delicate interlacing collagen fi bers, interspersed with large numbers of cellular elements and cementum-like hard tissues.<BR>Transmission electron microscopic findings: The tumor was found to consist of fibroblastlike cells, cementblast-like cells and hard tissues. The fibroblast-like cells assuming spindle or polyhedral shape, contained abundant cytoplasmic organelles and large nuclei. The nuclei varied from elongated ovoid shapes with smooth outline to polyhedral shapes with deep invagination. Intracytoplasmically, there were well developed rER, Golgi apparatus and several mitochondria. Some cementoblast-like cells also contained abundant amounts of 10 nm filaments and 10-400 nm electron-dense microgranules. The intracytoplasma of these cells usually contained electron-dense deposits and needle-shaped crystal-like structures. Within the fibrous matrix, amorphous electron-dense deposits on the collagen fiber bed were usually noted. Occasionally a small number of matrix vesicle-like structures were also present on the collagen fi bers. These matrix vesicle-like structures included electron-dense deposits or needle-shaped crystal like structures.<BR>Scanning electron microscopic findings: In the collagen fibrous matrix, there were numerous rounds or ovoid, structureless calcified clusters and cellular elements. Early calcifying deposition on the delicately interlacing fibrous network could also be observed around the cementum-like structure. Occasionally, coalescence of a round calcifying structure into a large cluster was also observed.<BR>X-ray microanalysis revealed that these clusters contain a high concentration of phosphate and calcium.
社団法人日本口腔外科学会の論文

Cementifying fibroma of the mandible. Report of a case with electron microscopic observation.:Report of acase with electron microscopic observation

スポンサーリンク

概要

著者

関連論文

スポンサーリンク