小唾液腺の Plasmacytoid myoepithelioma-軟口蓋に生じた1症例とその文献的考察-

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Myoepithelioma is a rare salivary gland neoplasm. Histologically, the tumor is composed of spindle-shaped and/or plasmacytoid cells.<BR>Plasmacytoid myoepithelioma of the soft palate was reported in a 53-year-old man. The tumor, measuring 35×25×5 mm, was located on the left side of the soft palate and was surgically removed. Two years later, the patient has not experienced recurrence.<BR>Microscopically, the tumor consisted of plasmacytoid cells with round eccentric nuclei surrounded by an abundant homogenous eosinophilic cytoplasm in myxoid stroma.<BR>Immunohistochemical studies revealed positive reactions for S-100 protein and vimentin in tumor cells. Electron microscopy demonstrated abundant intermediated filaments filled with tumor cells.<BR>A review of the literature indicated that plasmacytoid myoepitheliornas appearred to have a predilection for the oral cavity in younger individuals, while the spindle-cell form tends to occur in the parotid gland in older patients.
社団法人日本口腔外科学会の論文