口腔内に初発症状を呈した Wegener 肉芽腫症の1例-症例報告および文献的考察-

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Although the mouth is often involved in Wegener's granulomatosis (WG), oral lesion as the initial sign is rare.<BR>The differential diagnosis of WG is difficult, especially in the limited form of the disease. In this paper, we report a case of early WG in which oral and nasal lesion is presented at the beginning of his illness. In addition, we review the reports of WG with oral manifestations, and the classification of WG from other "midline destructive lesions" is discussed. The oral manifestation of WG have received much attention in several journals, which may lead to early diagnosis.<BR>The use of immunosuppressive drugs, which is particularly cyclophosphamide, have greatly enhanced prognosis, especially it is when treatment is started before renal involvement. The dentist and oral surgeon may, therefore, be very influential in determining prognosis.
社団法人日本口腔外科学会の論文