血小板輸血不応状態の再生不良性貧血患者にγ-グロブリン製剤を用いて抜歯を行った1例

概要

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We extracted a large number of teeth in a patient with severe aplastic anemia, who had not responded to conventional therapy and was in platelet-transfusion refractor, status as result of repeated platelet-transfusions. As a general hemostatic measure for postextraction bleeding, high doses of gamma-globulin were intravenously injected to enhance the response to platelet-transfusion.<BR>Pressure hemostasis using a surgical guide plate and sutures were applied for local hemostasis. Antibiotics were administered by intravenous drip infusion to prevent infection during and after the operation. Consequently, good healing without postextraction abnormal bleeding and infection was obtained. This treatment is therefore considered to be effective in such cases.
社団法人日本口腔外科学会の論文