NF-1の症状を認めない悪性神経鞘腫の2例

概要

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We report two cases of a malignant Schwannoma without NF-1. The first case was a 78-year-old female who presented with an elastic-hard, subcutaneous tumor on her left back area. In 1992, when she was 73 years old, the first resection was performed. In 1996, forty months after the first resection, it recurred locally without distant metastasis when she was 76 years old. After the second surgery, the tumors origin was the accessory nerve based on surgical findings and post-operative clinical symptoms. In 1998, when she was 78 years old, lung metastasis was recognized.The second case was a 59-year-old male who presented with an elastic-hard tumor on his left thigh area. When he was 48 years old, he developed a bruise on his left leg. The tumors origin was the lateral femoral cutaneous nerve based on surgical findings. Long-term follow-up is necessary for patients with malignant schwannoma with or without NF-1. [Skin Cancer (Japan) 2001; 16: 289-294]
日本皮膚悪性腫瘍学会の論文
2001-12-28