Bowen 病33例の臨床検討

概要

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Thirty patients who were histologically diagnosed as having Bowen's disease and 3 patients with Bowen's cancer, a total of 33 patients, were clinically examined. They were examined in this department in 5 years from January 1994 through December 1998. The average number of cases per year were 8.8 and the average age was 71.5 years. The ratio of males to females was 2: 3 and the number of female patients were more. A single focus was found in 28 cases and multiple foci were found in 5 cases. the prevalent site of occurrence was the inferior limb and found in 11 cases. The occurrence in exposed regions was rare and found in 6 cases. The size of lesion was 1-1.5cm in diameter in 27 cases. As to the suffering period, about 1 year was found in 14 cases and the largest. Regarding the treatment, excision with 0.5cm margin was performed on 26 cases of Bowen's disease and that with 1.0cm margin on 3 cases of Bowen's cancer. No relapse has been found. In 1 case who underwent excision without taking margin, recurrence occurred after 2 years. HPV was examined in 28 cases using anti-HPV polyclonal antibody, and every case was found negative.