皮膚転移を繰り返すも, 緩徐な経過を示す悪性黒色腫の1例

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We report a case of malignant melanoma who survived for 5 years with multiple skin metastases.The patient was a 85-year-old female.She noticed black macula on her rt. sole in March 1993.The lesion was resected and rt. groin dissection was performed. Histological examination revealed malignant melanoma (MNtype pT3N1M0 Stage III), and she recieved DAV (DTIC, ACNU, VCR) therapy before and after the operation.On June 1994, after DAV therapy, we recognized in-transit metastasis on her rt. groin.At first, skin metastases were limitted to rt. lower leg, but slowley extended to 1t. lower leg, abdomen, chest, both thighs and 1t. knee. So skin metastases were resected frequentry and many kinds of chemotherapeutics were applied. As the metastases were limited to the skin and subcutaneous tissues, she has survived for 5 years.