A CLINICAL PATHOLOGICAL STUDY ON THE PATTERNS OF DEVELOPMENT OF GASTRIC CANCER OF BORRMANN 4 TYPE:With Special Reference to the Pictures of Lymphatic Permiation

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Fifty-four patients with gastric cancer of Borrmann-4 type (defined the flat and diffusely infiltrative carcinoma with neither rand wall nor deep ulcer) resected at our depertment and other affiliated hospitals were investigated from the clinical and pathological viewpoints, together with the patterns of their developments. The results were as followed.1) In terms of the patterns in aggravation of gastric cancer of this type (Borrmann 4 type), two forms were found out, one is Type (A) in which carcinomatous cells infiltrate through the space of tissues with no reactivity and with association of lymphangitis carcinomatosa, preceded mainly by lymphatic spreading, and the other type (B) in which carcinomatous cells infiltrate through the space of tissues in association with fibrosis, preceded mainly by peritoneal disseminated development.2) In gross identification, Group A was often detected in the negative giant fold form of the irregular type, while Group B was often detected in the belt type, and positive giant fold form of irregular type.3) In terms of prognosis, those of developments of Group A had extremely poor prognosis in comparison with Group B.
財団法人日本消化器病学会の論文