A Case of Hepatitis C-Associated Osteosclerosis with Xanthogranulomatous Cholecystitis
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概要
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A 62-year-old woman presented with a markedly increased serum ALP level of skeletal origin during a regular follow-up of chronic hepatitis C. Serum calcium, phosphorus, and intact-PTH levels were normal and bone turnover markers were increased. Her generalized bone density was diffusely increased. These findings were consistent with hepatitis C-associated osteosclerosis (HCAO). She underwent cholecystectomy, as gallbladder cancer was suspected; however, histopathological findings demonstrated xanthogranulomatous cholecystitis. After cholecystectomy, serum ALP level and bone turnover markers were gradually decreased. This may indicate the existence of a novel osteogenic factor in the gallbladder in HCAO.
著者
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Morimoto Taisuke
Department Of Endodontics School Of Dentistry Aichi-gakuin University
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Hataya Yuji
Department Of Endocrinology And Metabolism Shizuoka Hospital
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Komatsu Yasato
Department Of Medicine And Clinical Science Graduate School Of Medicine Kyoto University
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CHUSHO HIDEKI
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
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Shintani Hiroyuki
Department of Gastroenterology, Kyoto City Hospital, Japan
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Kirishima Toshihiko
Department of Gastroenterology, Kyoto City Hospital, Japan
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Komatsu Yasato
Department of Endocrinology, Kyoto City Hospital, Japan
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Chusho Hideki
Department of Endocrinology, Kyoto City Hospital, Japan
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