A Case of Marinesco-Sjögren Syndrome: MRI Observations of Skeletal Muscles, Bone Metabolism, and Treatment with Testosterone and Risedronate
スポンサーリンク
概要
- 論文の詳細を見る
Marinesco-Sjögren syndrome (MSS) is a rare autosomal recessive disorder characterized by cerebellar ataxia, congenital cataracts, mental retardation, primary hypogonadism, skeletal abnormalities and myopathy, and patients with MSS are considered to be at risk of falls and bone fractures. We report a patient with MSS who received testosterone replacement therapy and risedronate administration. Muscle strength and the MRI features of the skeletal muscles were not changed, but low bone mass was improved by these treatments, and improvement has continued after risedronate treatment alone. This case suggests that treatment of MSS-related low bone mass using bisphosphonates is likely beneficial.
著者
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Mizuta Haruo
Department Of Clinical Science And Medicine Kyoto University Graduate School Of Medicine
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Hataya Yuji
Department Of Endocrinology And Metabolism Shizuoka Hospital
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Komatsu Yasato
Department Of Medicine And Clinical Science Graduate School Of Medicine Kyoto University
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Fujitake Junko
Department of Neurology, Kyoto City Hospital, Japan
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Nishikawa Atsuko
Department of Neurology, Kyoto City Hospital, Japan
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Eriguchi Makoto
Department of Internal Medicine, Faculty of Medicine, Saga University, Japan
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Hayashi Michiyuki
Department of Neurology, Kyoto City Hospital, Japan
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Komatsu Yasato
Department of Endocrinology, Kyoto City Hospital, Japan
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