EFFECT OF ESTRADIOL-17β ON THE METABOLISM OF PHOSPHOLIPIDS AND THEIR PRECURSORS IN RAT UTERUS
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概要
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The effect of estradiol-17β on the metabolism of phosphatidylethanolamine phosphatidylcholine in rat uterus was investigated in vitro by using 32Porthophosphate, 32P-phosphorylethanolamine, <SUP>32</SUP>P-phosphorylcholine, <SUP>32</SUP>Pphosphatidylethanolamine and <SUP>32</SUP>P-phosphatidylcholine as substrates.1.It was suggested that the biosynthesis of phosphorylethanolamine, phosphorylcholine, phosphatidylethanolamine and phosphatidylcholine was stimulated by estradiol-treatment.2.The incorporation of <SUP>32</SUP>P-phosphorylethanolamine into phosphatidylethanolamine was increased but that of <SUP>32</SUP>P-phosphorylcholine into phosphatidylcholine was not increased by the administration of estradiol-17β.The incorporation of phosphatidylethanolamine into phosphatidylcholine not affected by estradiol-17β and the reaction from phosphatidylcholine phosphatidylethanolamine was not observed.
- 社団法人 日本内分泌学会の論文
著者
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Aizawa Yoshio
Department Of Pharmacology Tokyo College Of Pharmacy
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NISHIGORI HIDEO
Department of Pharmacology, Tokyo College of Pharmacy
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NISHIGORI Hideo
Department of Pharmaceutical Therapeutics, School of Pharnmacy, Iwate Medical University
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