5α-Dihydrotestosterone “Receptor” in the Rat Hypothalamus
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概要
- 論文の詳細を見る
A 5α-dihydrotestosterone binding component, sedimenting with a sedimentation constant of 8.6S, was detected in rat hypothalamic cytosol labelled <I>in vitro</I> with 5α-dihydrotestosterone-3H. The dissociation constant of the androgen-protein complex and the number of binding sites of the component were approximately 7.4×10<SUP>-10</SUP>M and 0.9×10<SUP>-14</SUP> moles/mg cytosol protein, respectively. The binding component seemed to have a specificity for 5α-dihydrotestosterone relative to other hormones. These results suggest that the cytosol from male rat hypothalamus contains “receptor” for 5α-dihydrotestosterone.
- 社団法人 日本内分泌学会の論文
著者
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Kato Junzo
Department Of Obstetrics And Gynecology Yamanashi Medical College
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Onouchi Tsuneko
Department Of Clinical Research Teikyo University School Of Medicine
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Kato Junzo
Department Of Obstetrics And Gyleecology Yamanashi Medical University
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