5α-Dihydrotestosterone “Receptor” in the Rat Hypophysis
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概要
- 論文の詳細を見る
A 5α-dihydrotestosterone binding component, sedimenting in the 8 S region, was detected by sucrose gradient analysis in rat hypophyseal cytosol labelled <I>in vitro</I> with 5α-dihydrotestosterone-<SUP>3</SUP>H. The dissociation constant of the androgen-protein complex and the number of binding sites of the component were approximately 2.4×10<SUP>-9</SUP> M and 5.3×10<SUP>-14</SUP> moles/mg cytosol protein, respectively. The binding component seemed to have a specificity for 5α-dihydrotestosterone relative to other hormones. These results suggest that the cytosol from male rat hypophysis contains a “receptor” for 5α-dihydrotestosterone.
- 社団法人 日本内分泌学会の論文
著者
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Kato Junzo
Department Of Obstetrics And Gynecology Yamanashi Medical College
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Onouchi Tsuneko
Department Of Clinical Research Teikyo University School Of Medicine
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Kato Junzo
Department Of Obstetrics And Gyleecology Yamanashi Medical University
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ONOUCHI TSUNEKO
Department of Obstetrics and Gynecology, Teikyo University School of Medicine
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