Effects of Concanavalin A and Neuraminidase on Cyclic AMP Levels and <SUP>14</SUP>C-l-Glucose Oxidation in Dog Thyroid Slices
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概要
- 論文の詳細を見る
Treatment with concanavalin A at 100μg/m<I>l</I> or higher concentrations significantly increased <SUP>14</SUP>C-1-glucose oxidation in dog thyroid slices as reported in other tissues. This treatment exerted no effect on tissue cyclic AMP levels.<BR>Neuraminidase at the same concentrations also had similar effects on these parameters.<BR>Neither concanavalin A nor neuraminidase at the concentrations up to 100μg/m<I>l</I> had the TSH effect on both tissue cyclic AMP and <SUP>14</SUP>C-1-glucose oxidation.<BR>These results indicate that modification of carbohydrate moieties of glycoproteins on the cell surface may cause an increase in glucose metabolism without any critical effect on cyclic AMP system and in the process of TSH response.
- 社団法人 日本内分泌学会の論文
著者
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Aiyoshi Yuji
Department Of Surgery Institute Of Clinical Medicine University Of Tsukuba
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Ogata Etsuro
Department Of Internal Medicine Cancer Institute Hospital
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Oka Hiroshi
First Department Of Internal Medicine Tokyo University
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Yamashita Kamejiro
Department Of Internal Medicine Institute Of Clinical Medicine University Of Tsukuba
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AIYOSHI YUJI
Department of Medioine, University of Tsukuba
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OKA HIROSHI
First Department of Medicine, University of Tokyo
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YAMASHITA KAMEJIRO
Department of Medioine, University of Tsukuba
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