ON THE FUNCTIONAL CORRELATION BETWEEN SALIVARY LANDS AND OTHER ENDOCRINE ORGANS V. CHANGES IN RAT SALIVARY GLANDS FOLLOWING THYROIDECTOMY, ADMINISTRATION OF ANTITHYROID DRUGS AND THYROXINE-TREATMENT : STUDIES ON THE PHYSIOLOGICAL CHEMISTRY OF THE SALIVARY
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概要
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Thyroidectomy markedly inhibited the weight increase of the salivary glands, especially the submaxillary glands of rats and the simultaneous administration of thyroxine to the thyroidectomized animals could make the salivary glands to recover the normal control level. Nucleic acid in the submaxillary glands was markedly decreased by thyroidectomy and recovered to its normal value by administration of thyroxine. The inhibition of the weight increase of the salivary glands caused by administration of antithyroid drugs; methylmercaptoimidazole or methylthiouracil, was also prevented by thyroxine. The study made to know the mode of action of methylmercaptoimidazole suggested that this antithyroid drug has no direct action on the salivary glands.
- 社団法人 日本内分泌学会の論文
著者
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KAWADA JUN
Department of Biochemistry, Faculty of Pharmaceutical Sciences, The University of Tokushima
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KAWADA JUN
Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, University of Tokyo
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Kawada J.
Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, University of Tokyo
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