魚類感染症に対するPotassium-1-methyl-1, 4-dihydro-7-[2-(5-nitro-2-furyl)-vinyl]-4-oxo-1, 8-naphthyridine-3-carboxylic acid (DSー677 K) の化学療法的研究

概要

論文の詳細を見る
The authors investigated the potencies of some chemotherapeutics against infectious diseases in fish as observed in some breeding farms for marine or fresh water fish. Potassium-1-methyl-1, 4-dihydro-7-[2-(5-nitro-2-furyl)-vinyl]-4-oxo-1, 8-naphthyridine-3-carboxylic acid (DS-677 K) showed an excellent in vitro bactericidal effects against fish pathogens which cause some types of serious diseases in fish. Furthermore, the antibacterial activity of this agent did not change with temperature. However, its activity became reduced rapidly by sun light. Though tissue levels of this compound were low, chemotherapeutical effects in eel and gold fish, infected with A. liquefaciens, were higher than those of DF or TC which were used as control drugs.
公益社団法人日本水産学会の論文