Cytogenetic effects of quercetin on cultured mammalian cells.
スポンサーリンク
概要
- 論文の詳細を見る
Quercetin, a ubiquitous flavonoid, was found to induce chromosome aberrations and sister chromatid exchanges (SCEs) in cultured human and Chinese hamster cells without the application of metabolic activation systems. The increment in the frequency of SCEs was dose dependent, the maximum rates being 1.7-3.3 times the control values. The frequency of chromosome aberrations was elevated up to 1.5-7.8 times the highest control level, although clear dosage effects were obtained only in Chinese hamster cells.
- 日本学士院の論文
著者
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SASAKI MOTOMICHI
Chromosome Research Unit, Faculty of Science, Hokkaido University
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YOSHIDA Mitsuaki
Chromosome Research Unit, Faculty of Science, Hokkaido University
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SUGIMURA Keiko
Chromosome Research Unit, Faculty of Science, Hokkaido University
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KAWACHI Takashi
National Cancer Center Reserach Institute
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KAWACHI Takashi
National Cancer Center Research Institute
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