Experimental central serous chorioretinopathy IV Fluorescein angiography and electron microscopy during spontaneous healing process.:IV : Fluorescein Angiography and Electron Microscopy During Spontaneous Healing Process

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Spontaneous healing processes of experimental central serous chorioretinopathy induced by repeated intravenous adrenalin injections were studied in detail by fluorescein angiography and electron microscopy. The abnormal fluorescein spot in this experimental model changed from the initial ink blot type into the residual type and, further, into the window defect type, before finally disappearing. These findings indicate that the healing process in our model closely resembles those in human. Further, the histological findings suggest that the spot of either residual type or window defect type identified by fluorescein angiography is due to marked enlargement of basal infoldings of pigment epithelial calls and separation of the intercellular gap junction between the pigment epithelial cells; furthermore, the difference between the two types of fluorescein spots depends on the difference in. the degree of such morphological changes, mentioned above.
久留米大学医学部 The Kurume Medical Journal 編集部の論文