West Syndrome Associated with Administration of a Histamine H1 Antagonist, Oxatomide
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概要
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We report a 4-month-old female infant who developed West syndrome eleven days after administration of a histamine H<SUB>1</SUB> antagonist, oxatomide, for atopic dermatitis. It has been reported that some histamine H<SUB>1</SUB> antagonists induce seizures in epileptic patients. The age, the interval between oxatomide administration, and the onset of West syndrome and its clinical course were similar to two previously reported 3-month-old infants with West syndrome associated with ketotifen administration. We should be cautious in using the histamine H<SUB>1</SUB> antagonists, oxatomide and ketotifen, in young infants because such agents could potentially disturb the anticonvulsive central histaminergic system.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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Yamashita Yushiro
Department Of Pediatrics & Child Health Kurume University School Of Medicine
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Seki Yoshitaka
Department Of Applied Materials Science Muroran Institute Of Technology
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Ohya Takashi
Department Of Cardiovascular Surgery Mitoyo General Hospital
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NAGAMITSU Shinichiro
Department of Pediatrics & Child Health, Kurume University School of Medicine
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MATSUISHI Toyojiro
Department of Pediatrics & Child Health, Kurume University School of Medicine
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ISAGAI TAKEO
Department of Pediatrics and Child Health, Kurume University School of Medicine
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