A case of eosinophilic fasciitis with eosinophil infiltration in the lungs.

概要

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We described a patient of eosinophilic fasciitis with eosinophil infiltration in the lungs. The patient was a 23 years old female who developed bilateral swollen and painful legs, and peripheral blood eosinophilia after the episode of upper respiratory infection. A wedge biopsy of the leg revealed thickned fascia and remarkable eosinophil infiltration in the perimyosium. Transbronchial lung biopsy showed significant infiltration of eosinophils in the alveoli and alveolar walls, although the chest X-ray showed only slight infiltrationshadows and pulmonary function test were within normal limits. This case was diagnosed to have eosinophilic fasciitis by the findings of bilateral swollen and painful legs, and peripheral blood eosinophilia, and the characteristic biopsy findings of the fascia. Until now eosinophilic fasciitis associated with lung involvement has not been reported. Thus, this case was of note to study a new spectrum of eosinophilic fasciitis.
日本臨床免疫学会の論文