An assessment of cellular immunity using delayed hypersensitive skin tests: II:multiple skin tests of malignant diseases

概要

論文の詳細を見る
One hundred and fifty one patients with various malignant diseases were tested with 4 types of delayed hypersensitive skin tests (PPD, PHA, Candida and SK-SD) and evaluated their nutritional status by hemoglobin, lymphocyte, serum albumin and ratio of weight to height before operation. The skin test index was calculated by using an equation: STI=logDT+logDC+logDP+logDS-0.4/4(DT, DC, DP, DS: mean diameter of PPD, PHA, Candida and SK-SD).The STI was compared with nutritional parameters using linear regression.The following results were obtained:1. Subnormal response, namely, STI smaller than 1.0, existed in 44% of respiratory malignant diseases, 39% with digestive malignant diseases and 47% with other malignant diseases.2. STI was well related with hemoglobin, serum albumin and ratio of weight to height in the respiratory malignant diseases.3. STI was well related with lymphocyte in the digestive malignant diseases.4. STI was well related with serum albumin and ratio of weight to height in the other malignant diseases.5. The depressed STI in malignant diseases were well related with operability.
日本臨床免疫学会の論文